Increasing Diagnostic Value of Transbronchial Lung Cryobiopsy

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Diagnostic yield of transbronchial lung cryobiopsy in interstitial lung diseases.

Surgical lung biopsy (SLB) is still considered the gold standard procedure to obtain histology in interstitial lung diseases (ILD), the final diagnosis being decided on the basis of multidisciplinary assessment. The availability of a histological pattern may be very important in reaching diagnosis, predicting outcome and responding to treatment. There has been an increasing interest on transbro...

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Diagnostic yield of transbronchial cryobiopsy in non-neoplastic lung disease

Due to the small amount of alveolar tissue in transbronchial biopsy (TBB) by forceps, the diagnosis of diffuse, parenchymal lung diseases (DPLD) is inherently problematic, with an overall low yield. The use of cryotechnique in bronchoscopy, including TBB by cryoprobe, has revealed new opportunities in the endoscopical diagnosis of malignant and non-malignant lung diseases. To evaluate TBB by cr...

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Transbronchial lung cryobiopsy: Associated complications.

INTRODUCTION Transbronchial lung cryobiopsy (TBC) has emerged as a diagnostic alternative to surgical lung biopsy in interstitial lung disease (ILD). Despite its less invasive nature, some associated complications have been described. OBJECTIVE To evaluate complications of TBC and associated factors. METHODS Prospective evaluation of all patients with ILD submitted to TBC in our centre. Cli...

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Transbronchial cryobiopsy in diffuse parenchymal lung disease

The evaluation of patients with diffuse parenchymal lung diseases (DPLD), particularly the idiopathic interstitial pneumonias (IIP), often requires a multidisciplinary team approach. A surgical lung biopsy may be necessary for a confident diagnosis, particularly in patients with atypical clinical/radiological presentations.1 However, surgical lung biopsies carry a risk of serious complications,...

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Learning curve for transbronchial lung cryobiopsy in diffuse lung disease.

INTRODUCTION Transbronchial lung cryobiopsy (TBLC) is increasingly used in the diagnosis of diffuse lung disease (DLD), but no data have yet been published on the learning curve associated with this technique. AIM To evaluate diagnostic yield, lung tissue sample length and area, and procedure-related complications in a cohort of TBLC procedures to define the learning curve and threshold for p...

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ژورنال

عنوان ژورنال: Respiration

سال: 2016

ISSN: 0025-7931,1423-0356

DOI: 10.1159/000445123